The Command Preferences pane affects the behavior and contents of the Available Commands window, as well as what commands are actually available.
Check Show Global Commands at Top to make the global commands appear above the application-based commands in the Available Commands window.
Check Enable Web Site Commands to cause the Web 100 global commands to be enabled (and to be present in the Available Commands window).
Check Generate Application Launch Commands to cause global commands for launching applications to be generated the next time you start up Dragon Dictate.
Check Generate Email Commands to cause global commands for creating and addressing an email message to be generated the next time you start up Dragon Dictate.